Pharmacodynamics flufenicol bụ ọgwụ nje dị iche iche.
Nke aminools, bacteriosuppressor, ma na-eme site na ijikọ na ribosome 50s subunit iji gbochie njikọ nke protein nje. Ọ nwere ọrụ antibacterial siri ike megide ụdị nje bacteria gram-positive na gram-adịghị mma. Pasteurella hemolyticus, pasteurella multocida na actinobacillus suis pleuropneumoniae nwere mmetụta dị ukwuu na flufenicol. Na vitro, ọrụ antimicrobial nke flufenicol megide ọtụtụ microorganisms yiri ma ọ bụ siri ike karịa nke sulfonicol, na ụfọdụ nje bacteria na-eguzogide aminools n'ihi acetylation, dị ka escherichia coli na klebsiella pneumoniae, nwere ike ka na-enwe mmetụta nke flufenicol.
A na-ejikarị ya maka ọrịa nje nke ezì, ọkụkọ na azụ nke nje bacteria na-emetụ n'ahụ kpatara, dị ka ọrịa iku ume nke anụ ụlọ na ezì nke pasteurella hemolyticus, pasteurella multocida na actinobacillus pleuropneumoniae kpatara. Typhoid na paratyphoid kpatara salmonella, ọgbụgbọ ọkụkọ, ọnyụnyụ ọcha ọkụkọ, colibacillosis, wdg; azụ pasteurella, vibrio, staphylococcus aureus, hydroomonas, enteritis na ndị ọzọ nje bacteria kpatara azụ nje septicemia, enteritis, erythroderma na anya.
Pharmacokinetics flufenicol na-etinye obi ya ngwa ngwa site na nchịkwa ime, yana enwere ike ị nweta mkpokọta ọgwụgwọ n'ime ọbara mgbe ihe dị ka elekere 1 gachara, yana enwere ike iru ogo ọbara kacha elu n'ime awa 1 ruo 3. The bioavailability bụ ihe karịrị 80%. A na-ekesa Flufenicol n'ọtụtụ ebe n'ime anụmanụ ma nwee ike ịgafe ihe mgbochi ụbụrụ ọbara. A na-ewepụ ya na mmamịrị n'ụdị mbụ ya na obere ntakịrị na nsị.
1. Macrolides na lincoamines nwere otu ebumnuche dị ka ngwaahịa a, a na-ejikọta ha na nje bacteria ribosome 50s subunit, ma nwee ike ịmepụta mmetụta na-emegide ya mgbe ejikọtara ya.
2. Ọ nwere ike imegide ọrụ nje nke penicillins ma ọ bụ aminoglycosides, mana egosibeghị ya na anụmanụ.
Ọgwụ nje Amidoalcohol, nke nwere mmetụta dị ukwuu na Pasteurella hemolyticus, Pasteurella multocida na actinobacillus pleuropneumoniae, ejiri maka ọrịa Pasteurella na Escherichia coli.
Intramuscular injection: otu dose, kwa 1kg arọ ahu, 0.2ml maka ọkụkọ, 0.15 ~ 0.2ml maka atụrụ na ezi, 0,075 ~ 0.1ml maka ịnyịnya na ehi. Otu ugboro kwa awa 48, ugboro abụọ n'usoro. Azụ 0.005 ruo 0.01ml otu ugboro n'ụbọchị.
1. Ngwaahịa a nwere ụfọdụ mmetụta immunosuppressive mgbe ejiri ya dị elu karịa ọgwụ akwadoro.
2. O nwere nsi nwa ebu n'afọ, ekwesịrị iji nlezianya mee ya n'oge ime ime na anụ ụlọ.
1. Amachibidoro ịtọgbọ ọkụkọ.
2. Anụmanụ ndị nwere ụkọ mgbochi ọrịa siri ike ma ọ bụ oge ịgba ọgwụ mgbochi kwesịrị ka amachibidoro.
3. Anụmanụ ndị nwere ụkọ gbasara akụrụ kwesịrị ibelata nke ọma ma ọ bụ ịgbatị oge nchịkwa nchịkwa.
