Pharmacodynamics ceftiofur bụ klas β-lactam nke ọgwụ nje na-egbu egbu, nke nwere nnukwu mmetụta nje bacteria, dị irè megide nje gram-positive na gram-adịghị mma (gụnyere β-lactamase na-emepụta nje bacteria). Usoro nje ya bụ igbochi njikọ nke mgbidi sel nje na-eduga na ọnwụ nke nje bacteria. The mwute bacteria bụ tumadi pasteurella multiplex, pasteurella hemolyticus, actinobacillus pleuropneumoniae, salmonella, escherichia coli, streptococcus, staphylococcus, wdg Ụfọdụ pseudomonas aeruginosa, enterococcus eguzogide. Ọrụ antibacterial nke ngwaahịa a siri ike karịa nke ampicillin, yana ọrụ megide streptococcus siri ike karịa fluoroquinolones.
Pharmacokinetics ceftiofur na-etinye uche ya ngwa ngwa yana ọtụtụ ebe site na intramuscular na subcutaneous injections, mana enweghị ike ịgafe mgbochi ụbụrụ ọbara. Ntinye nke ọgwụ ahụ dị elu n'ọbara na anụ ahụ, a na-echekwa ntinye ọbara dị irè ruo ogologo oge. Enwere ike imepụta metabolite desfuroylceftiofur na-arụ ọrụ n'ime ahụ, wee megharịa ya ka ọ bụrụ ngwaahịa na-adịghị arụ ọrụ nke a na-ewepụ na mmamịrị na nsị.
β-lactam ọgwụ nje. A na-ejikarị agwọ ọrịa nje nke anụ ụlọ na anụ ọkụkọ. Dị ka nje bacteria na-akpata iku ume na ọrịa ọkụkọ escherichia coli, ọrịa salmonella.
A na-eji Ceftiofur eme ihe. Ngwunye intramuscular: Otu dose, 1.1-2.2mg kwa 1kg arọ anụ ahụ maka ehi, 3-5mg maka atụrụ na ezi, 5mg maka ọkụkọ na ọbọgwụ, otu ugboro n'ụbọchị maka ụbọchị 3.
Inyocha subcutaneous: ụmụ ọkụkọ dị otu ụbọchị, 0.1mg kwa nku.
(1) Ọ nwere ike ịkpata ọgba aghara flora eriri afọ ma ọ bụ ọrịa okpukpu abụọ.
(2) Enwere ụfọdụ nephrotoxicity.
(3) Mgbu mgbu na-agafe agafe nwere ike ime.
(1) Jiri ugbu a.
(2) Ekwesịrị ịhazi dose ahụ maka ụmụ anụmanụ nwere ụkọ akụrụngwa.
(3) Ndị nwere mmetụta nke ukwuu maka ọgwụ nje beta-lactam kwesịrị izere ịkpọtụrụ ngwaahịa a ma zere ikpughe ụmụaka.
